Poor Artemis is wrapped in a straitjacket and locked in a room. What she doesn't know is Alexis is enduring the same fate right next door! Eventually, the gals figure out someone else besides the crazy nurse Dorothy is around by knocking on the wall between them. Dorothy finds that her two prisoners are communicating so she tries to keep them apart longer by binding them even more, but Alexis manages to get free and goes to the aid of Artemis. Once that's done, all they have to do is force Dorothy into a straitjacket of her own and then escape from The Institute.

After being chloroformed and kidnapped, Dorothy wakes up to find herself bound to a hospital bed and being watched by a sinister doctor. She is told that she took a bad fall, and although Dorothy thinks she feels fine, the doctor continues to monitor her. He gives her an injection to "calm her" but refuses to let her out of the restraints. When Dorothy gets too vehement about wanting to be let go, the doctor sends her to solitary confinement, where she is bound in a straitjacket, gagged, and left alone in a small space. She is finally let out...into the waiting clutches of her doctor, who strips and molests her. She fights back, but is made to suffer for it. She's hung by her ankles, while bound in the straitjacket with no one to let her down.